When your body's cells produce energy, they also create byproducts called reactive oxygen species (ROS). These can damage DNA in various ways, one of the most common being the oxidation of guanine, a building block of DNA. This oxidized form is known as 8-oxoguanine (8-oxoGua). If not fixed, 8-oxoGu
In India, the meniscus root tears — specifically the medial and lateral ones — are an issue that deserves special attention. These tears can happen due to various reasons and lead to different patterns of damage. Scientists wanted to learn more about why these tears occur and how they look in the In
Punctal agenesis, or PA, is a rare birth defect that might show up on its own or be part of a bigger syndrome. Scientists haven't really looked into how useful it is to check genes in people with PA and some specific symptoms. This study aimed to find out what eye and other body problems are linked
Did you know that light can influence your brain and mood? Scientists have found that shining infrared light on a specific part of the brain, called the hippocampus, can boost the growth of new brain cells. This part of the brain is linked to mood disorders, and growing new cells there can help redu
Ever wondered how bacteria stay alive inside your body? Salmonella, for one, has a clever trick up its sleeve. It uses two special enzymes, SIRT1 and SIRT3, to mess with your body's energy system. You might know these enzymes as sirtuins. They're like the body's metabolic regulators, helping to cont
Did you know that as mice age, they have fewer serotonin-producing neurons? These neurons are crucial for brain function and learning. Scientists found that older mice have fewer of these neurons in two key brain areas: the dorsal raphe nucleus (DRN) and the median raphe nucleus (MRN). This was espe
CapG, a key enzyme from Staphylococcus aureus, folds and unfolds in a complex dance. This protein, which helps the bacteria build its defence shield, changes shape based on its concentration and surroundings. Scientists studied a replica of CapG, called rCapG, and found it can exist in many forms, f
Imagine trying to understand how a building grows. It’s tricky without seeing the scaffold change and move. Similarly, scientists have been puzzled by how mammal hair follicles develop because they couldn’t clearly observe the basement membrane (BM)—the structure that supports and shapes the follicl
Cervical cancer, the most common gynecological cancer worldwide, is on the rise. Researchers are finding that certain viruses, like human papillomavirus (HPV), Epstein-Barr virus (EBV), and others, might be playing a part in this cancer's development. It's crucial to understand how these viruses int
In mice, a missing gene called H3t leads to more testicular somatic cells, specifically Leydig cells. These cells produce testosterone, but the increased numbers also show signs of aging. This suggests Leydig cells might play a role in monitoring and promoting sperm development, which is crucial for
