Multiple sclerosis (MS) causes increasing disability due to long-term inflammation in the brain and spinal cord. This ongoing inflammation, called smoldering neuroinflammation, is tough to treat with current medications. Chronic active white matter lesions are a big part of this problem. Initially, these lesions were only seen in autopsies. But now, we have advanceme...
Have you ever wondered how doctors check if people with multiple sclerosis (MS) are moving around safely? One tool they use is the Community Balance and Mobility Scale (CB&M). But how reliable and accurate is this scale? Scientists took a closer look to find out. Picture this: you're someone with MS, trying to move around your community. The CB&M scale is like a che...
Imagine you have multiple sclerosis (MS) and you're trying to learn a new physical task. A recent study looked into how three simple factors—autonomy, positive expectations, and focus on external cues—could help people with MS perform better and learn faster. Researchers divided 30 MS patients into two groups: one received special training (optimized group) and the o...
Ever wondered how our brain's white matter stays intact? In multiple sclerosis (MS), two proteins, Tyro3 and Gas6, are key players in maintaining this crucial tissue. These proteins are part of the Gas6/TAM system, which includes Tyro3, Axl, and Mer receptors. While animals have shown these proteins can slow down demyelination and speed up remyelination, human eviden...
Multiple sclerosis (MS) is a puzzle where the immune system mistakenly attacks the body's own nerves. We know that certain genes and outside factors kickstart this process, but the full picture remains blurry. While we've identified harmful T cells, the role of B cells – the antibody producers – is still a mystery. Understanding how these B cells contribute to nerve ...
In Italy, researchers recently took a close look at the financial burden of multiple sclerosis (MS) on patients receiving disease-modifying therapies (DMTs). They studied 393 MS patients, mostly women around 45 years old, with a form of MS called relapsing-remitting MS (RRMS). On average, each patient's yearly costs came to about €20, 300. Costs went up with the seve...
Exercise can slow down disability progression for people living with multiple sclerosis (MS). But what workouts do these individuals enjoy? And what tools do they need to make exercise a regular habit? This study dives into these questions by focusing on the personal preferences of Australians with mild MS. It's not just about the clinical side; it's about what makes...
Selma Blair, known for her roles in movies like "Cruel Intentions" and "Legally Blonde, " recently made an appearance at the Elle Women in Hollywood event. She showed up in a stylish white dress and heels, leaving behind her walking cane and service dog, which had become her companions over the past few years due to multiple sclerosis (MS). "I've been feeling much be...
Do you know that multiple sclerosis (MS) can affect your brain in different ways? People with progressive MS (PMS) might face a unique set of challenges compared to those with relapsing-remitting MS (RRMS). Scientists are still trying to figure out if PMS patients have a distinct pattern of brain issues, known as cognitive impairment (CI), and if their brains decline...
Multiple sclerosis (MS) is a tricky disease that doctors are still trying to understand. One important protein linked to MS is CHI3L1, which plays a big role in inflammation and tissue repair. Scientists have come up with a clever way to measure this protein using a sandwich ELISA method. The key to this new approach is gold nanoparticles, which are tiny gold bits ma...