A Fresh Look at Managing Lennox-Gastaut Syndrome

Lennox-Gastaut syndrome (LGS) is a tough-to-treat type of epilepsy that often starts in childhood and sticks around. It's known for many types of seizures, especially tonic ones, which can make people fall and hurt themselves. Plus, it comes with learning difficulties and behavior issues. Doctors recently got together to update how to handle LGS, focusing on new medicines and therapies. The first step is usually valproate, but if that doesn't work, other medicines like lamotrigine and rufinamide can be added. If seizures are still a problem, there are more options. The goal is to find the best combination for each person, using no more than two medicines at a time. Along with medicines, non-drug treatments like special diets and brain stimulation can help. Doctors should check in with patients at least once a year to make sure they're on the right track. The idea is to improve seizure control and quality of life, even though LGS is hard to manage.