A Fungus Fighting Cancer: Cordycepin's Secret

Nottingham, UKTue Nov 12 2024
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Ever heard of a caterpillar fungus? It's a weird little organism that takes over caterpillars. Turns out, it might help fight cancer! Scientists at the University of Nottingham, UK, have found a special compound in this fungus, called cordycepin, that could stop cancer cells from dividing out of control. This fungus has been used in traditional Chinese medicine for ages, but now we're starting to understand how it really works. Cordycepin tricks cells into thinking it's a part of them. Once inside, it changes into something called cordycepin triphosphate. This molecule messes with the cell's growth signals, making cancer cells stop dividing. That's a big deal because cancer cells usually divide too much, which is what makes tumors grow.
Unlike chemotherapy, which can hurt healthy cells, cordycepin targets only the cancer cells. That means it could be less harmful to the body. Plus, scientists can now track how cordycepin affects patients by looking at certain genes in blood cells. The lead researcher, Cornelia de Moor, has been studying cordycepin for years. She's excited because these experiments are getting easier and cheaper. That means we can learn more about how cordycepin works and maybe even make new drugs from it.
https://localnews.ai/article/a-fungus-fighting-cancer-cordycepins-secret-c747eb2d

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