SCIENCE

A New Way to Sort Molecules for Safer Medicines

Thu Jul 03 2025
In the world of medicine, molecules can be tricky. Some look almost the same but behave very differently. This is especially true for chiral molecules, which are like mirror images of each other. One version can be helpful, while the other might be harmful. So, finding a good way to separate them is really important. Scientists have come up with a new method to do this. They took a common amino acid called L-lysine and added a special ring to it. This ring helps the amino acid stick to other molecules in a specific way. Then, they mixed it with copper to create a special material called NLMOF. This material is like a tiny sponge that can catch and separate different chiral molecules. They tested it with 10 different amino acids and one medicine. The results were really good. The method was reliable and could be used many times without breaking down. What makes this method special is that it is easy and cheap to make. It doesn't need any harsh chemicals or complicated steps. This makes it a good choice for making medicines on a large scale. But why is this important? Well, when we take medicine, we want to make sure it's safe and effective. This new method helps ensure that only the good version of the molecule is used. This can make medicines safer and more reliable.

questions

    If NLMOF can separate chiral drugs, can it also help you decide which twin to blame for mischief?
    What are the potential limitations of the NLMOF method in large-scale industrial applications?
    Are the 'green ambient stirring conditions' just a cover for a more sinister, undisclosed chemical process?

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