An Uncommon Tumor: What Happened to a 59-Year-Old Woman

A 59-year-old woman faced an unusual health challenge when doctors discovered a malignant solitary fibrous tumor (MSFT) in her occipital region. This type of tumor is quite rare, and in her case, it exhibited an epithelioid pattern. Advanced tests like Next-generation sequencing (NGS) revealed a unique subtype known as NAB2ex7-STAT6 exon15/16 double fusion. Additionally, immunohistochemistry (IHC) showed strong positive expression of STAT6. Her medical team closely monitored her for any signs of recurrence, but luckily, she remained tumor-free for 20 months after surgery. The moral of the story is that while rare, these tumors can be managed effectively with the right diagnosis and treatment. To better understand this disease, experts reviewed the tumor's morphological and genetic features. They also considered various other conditions that could be mistaken for MSFT, ensuring a accurate diagnosis.