SCIENCE

Denisovans: Ancient Allies in Our Fight Against Germs

EastSoutheast AsiaWed Sep 10 2025

Denisovans, long-gone relatives of modern humans, left a lasting mark on our DNA. Their genes are still present in people from East and Southeast Asia. But how did the places they lived shape our ability to fight off diseases? That's the question scientists set out to answer.

Exploring Denisovan Habitats

Researchers looked at three spots where Denisovans once lived. These places had cold winters and warm summers. They checked if these areas were home to certain germs and the creatures that spread them.

  • Disease Presence:
  • Rare: Diseases spread by mosquitoes.
  • Common: Lyme disease.

Genetic Clues from Melanesia

Today, people in Melanesia have a lot of Denisovan genes. However, they don't have the ticks that spread Lyme disease. This suggests that Denisovans might have given us genes to fight off other diseases, like those spread by mosquitoes.

Cobra Cave in Laos

One Denisovan site, Cobra Cave in Laos, was suitable for many diseases. This could mean that Denisovans living there had to deal with a lot of different germs. Their genes might have helped them—and now us—survive in these tough environments.

Unanswered Questions

  • The study only looked at a few diseases and places.
  • There's still a lot we don't know about how Denisovans shaped our ability to fight off germs.

Conclusion

Despite the gaps in knowledge, it's a fascinating glimpse into our past and how it affects our health today.

questions

    What are the potential biases in the selection of the three Denisovan archaeological sites and how might they affect the study's conclusions?
    Could the genetic resistance to infections in modern humans be a result of a secret Denisovan survival technique that has been hidden from mainstream science?
    If Denisovans were around today, would they be more likely to catch a cold in a boreal forest or a tropical beach?

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