Diclofenac and COVID-19: Pharmacists' Role in Safe Medication Use

Diclofenac, a popular nonsteroidal anti-inflammatory drug (NSAID), has been a topic of concern during the COVID-19 pandemic. This is because it can worsen the disease by causing oxidative stress and mitochondrial problems. COVID-19 is known for its hyperinflammation, and diclofenac might make this worse. Additionally, it can increase the risk of heart problems like heart attacks and strokes, which are already a concern in COVID-19 patients. It can also harm the liver, especially in people with liver issues or those at higher risk due to COVID-19.Pharmacists are essential in managing these risks. They can review medications and assess risk factors to guide patients and clinicians toward safer options like ibuprofen or naproxen. Educating patients about diclofenac's side effects, such as heart symptoms, kidney problems, and liver issues, is crucial. Pharmacists can also advise on lifestyle changes and additional therapies to reduce dependence on NSAIDs. They play a vital role in monitoring patients for adverse drug reactions and reporting safety issues to improve NSAID usage guidelines during the pandemic. By taking a personalized approach, pharmacists can minimize risks and enhance patient safety, improving outcomes in managing COVID-19 and other inflammatory conditions.