SCIENCE

Differences in Atractylodes Species: A Closer Look at Their Polysaccharides

Sun Oct 12 2025

Atractylodes plants, renowned for their medicinal properties, encompass three primary species:

  • Atractylodes lancea (AL)
  • A. chinensis (AC)
  • A. macrocephala (AM)

These species contain unique polysaccharides, which significantly contribute to their medicinal attributes. Scientists have delved into these sugars to discern the distinctive characteristics of each species.

Molecular Size Matters

The size of the sugar molecules varies among the species:

  • AM possesses larger sugar molecules compared to AL and AC.
  • This size disparity serves as a crucial differentiator for AM.

Diversity in Sugar Types

The variety of sugars present in each species is notable:

  • AC boasts the most diverse range, with seven different types of sugars.
  • AL contains fewer sugars, setting it apart from AC.

Linkage Patterns: A Key to Distinction

The manner in which these sugars are linked is also pivotal:

  • Most sugars in all three species are linked via 1, 2-Fruf, indicating the prevalence of fructan.
  • AM uniquely contains a substantial amount of 1, 4-Galp, a linkage associated with pectin, suggesting a higher pectin content in AM compared to the other species.

Mathematical Analysis for Clear Differentiation

Utilizing advanced mathematical techniques, scientists could distinctly differentiate AL, AC, and AM based on their sugar linkages. Two specific linkages, 1, 4-Galp and 1, 2, 4-Rhap, played a significant role in this differentiation.

Conclusion

Understanding these differences sheds light on the potential variations in medicinal effects among the Atractylodes species.

questions

    If you mixed polysaccharides from AL, AC, and AM, would you get a super-polysaccharide that can solve world hunger?
    Can polysaccharides from AL, AC, and AM be used to create a new type of gluten-free bread?
    Could the higher content of monosaccharides in AC be a result of genetic modification, and if so, who is behind it?

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