HEALTH

Drugs and Kidney Risks: What You Need to Know

Sun Jul 06 2025

The Problem

  • Drugs in Question: Bevacizumab, ramucirumab, aflibercept
  • Known Side Effect: Proteinuria (excess protein in urine)
  • Unanswered Question: Can these drugs harm the kidneys?

Why It Matters

  • Purpose: These drugs treat cancer by inhibiting blood vessel growth.
  • Risk: Proteinuria may indicate kidney dysfunction.
  • Uncertainty: Is proteinuria a temporary side effect or a sign of kidney damage?

Current Knowledge

  • Studies Conducted: Insufficient to draw conclusions.
  • Information Needed:
  • Safety of these drugs for kidneys.
  • Methods to prevent kidney problems.

Call to Action

  • For Doctors:
  • Monitor patients closely.
  • Continue researching these drugs.
  • For Patients:
  • Discuss kidney health with doctors.
  • Report any side effects promptly.

questions

    Could the increased proteinuria be a deliberate design of these drugs to create a market for new kidney treatments?
    What are the implications of these findings for clinical practice, and how should healthcare providers balance the benefits and risks of these drugs?
    If these drugs cause so much proteinuria, should we start marketing them as the ultimate weight loss solution?

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