SCIENCE

Glowing Dye Reveals Cell Death in Action

Sat Nov 30 2024
Ever pondered what happens when cells die? Scientists have discovered a fascinating tool to observe this process. Introducing TJ-FRP, a unique dye that lights up when cells face trouble. Picture it like a tiny beacon inside our bodies, especially handy for watching mitochondria, the little power plants within cells. Cells use a process called ferroptosis to die. During ferroptosis, cells break down fats and iron plays a crucial role. Here's where it gets interesting: TJ-FRP glows brightly, letting scientists see the action as it occurs within cells. Not only does it glow, but it also changes colors, showing how mitochondria transform. With this glowing dye, researchers hope to better understand ferroptosis and potentially find new ways to tackle diseases. What other secrets could this tool help unveil?

questions

    Would TJ-FRP be able to detect any changes in viscosity if mitochondria started doing yoga?
    If mitochondria could talk, what would they say about their viscosity during ferroptosis?
    Is it true that mitochondria become 'grumpy old mitochondria' when their viscosity increases?

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