SCIENCE

How Genes and Environment Shape Our Personality

Sun May 25 2025
The connection between our genes and personality is a hot topic. One interesting angle is the role of genetic risk for schizophrenia. It turns out that having a high genetic risk for schizophrenia might influence personality traits in people who don't actually develop the disorder. This is not about causing schizophrenia but rather about how genes might shape who we are in more subtle ways. People often think of schizophrenia as a clear-cut condition. But the reality is more complex. Genes involved in schizophrenia might also play a role in shaping personality traits. This is where the Big Five personality traits come in. These are openness, conscientiousness, extraversion, agreeableness, and neuroticism. Researchers wanted to see if a person's genetic risk for schizophrenia could predict these traits. To explore this, scientists looked at something called polygenic risk. This is a measure of how many genes linked to schizophrenia a person has. They focused on individuals who did not have non-affective psychosis. This means they did not have schizophrenia or similar conditions. The goal was to see if there was a link between genetic risk and personality traits in these individuals. The study also compared the genetic risk for schizophrenia with the genetic risk for major depression. This was to check if any findings were specific to schizophrenia or if they applied more broadly to mental health risks. The idea was to see if the same genetic factors might influence personality traits in different ways. So, what does this all mean? It suggests that our genes might have a bigger role in shaping our personality than we thought. But it's not just about genes. Environmental factors also play a big part. The interplay between genes and environment is complex. Understanding this interplay could help us grasp how personality develops. It's important to note that having a high genetic risk for schizophrenia does not mean a person will develop the disorder. Instead, it might influence personality traits in subtle ways. This research opens up new questions about how genes and environment shape who we are. It's a reminder that our personalities are the result of many factors working together.

questions

    What are the implications of finding associations between PRSscz and personality traits for the understanding of mental health?
    Are polygenic risk scores being used to subtly influence personality traits in the general population?
    What are the potential confounding variables that might affect the relationship between PRSscz and personality traits?

actions