Is Malnutrition a Hidden Factor in Coronary Artery Disease?

Coronary artery disease (CAD) is a severe health problem worldwide, causing significant harm and death. While factors like oxidative stress, poor lipid management, and bad lifestyle choices are well-known contributors to CAD, recent studies show that immune responses and inflammation also play a role. Malnutrition, which can be changed, has a big impact on how CAD turns out. The prognostic nutritional index (PNI), created using serum albumin and lymphocyte count, helps forecast outcomes in many diseases. This study looks into how malnutrition, measured by the PNI score, is connected to the seriousness of coronary artery blockages, which are checked using fractional flow reserve (FFR) measurements. Doctors are interested in the PNI because it might help them decide if someone needs treatment for their heart disease. The PNI could be a useful tool for doctors to figure out who might benefit from procedures like stenting or bypass surgery. It's important to note that the PNI is not perfect and should be used along with other tests and information. Knowing more about the PNI could help doctors make better decisions and improve care for patients with CAD. However, more research is needed to understand how the PNI works in different situations and with different types of patients.