HEALTH

Kids and Pain Relief: The Ketorolac Dilemma

Thu Oct 09 2025

The Challenge with Ketorolac

Ketorolac is a powerful painkiller often administered to children via IV. Unlike opioids, it's a non-opioid pain reliever, making it a preferred choice in today's medical landscape. However, the optimal dose for children remains uncertain.

  • Current Practice: Most pediatric doses are extrapolated from adult doses.
  • The Problem: Children metabolize medications differently, meaning adult-based doses may not be as effective.

Variability in Hospital Practices

Different hospitals use varying doses, highlighting the lack of consensus. This inconsistency underscores the urgent need for more research.

Why It Matters

Children are not merely "small adults." Their bodies process medications uniquely, necessitating tailored dosing. With the medical community shifting away from opioids, accurate ketorolac dosing becomes even more critical.

The Impact of Effective Pain Management

Proper pain relief isn't just about comfort; it can enhance recovery and reduce anxiety for children and their families. Finding the right dose is essential.

The Path Forward

Researchers are working to gather the necessary data, but progress takes time. In the interim, doctors rely on educated guesses. More studies are needed to provide clear guidelines and ensure the best possible care for children.

questions

    How does the use of ketorolac compare to other nonopioid analgesics in children with acute pain?
    What are the ethical considerations in conducting randomized controlled trials with different doses of ketorolac in children?
    Could the pharmacokinetic differences between children and adults be exaggerated to justify higher doses of ketorolac?

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