Boosting Metal Powers with Quinols: A New Way to Fight ROS

Scientists have been exploring how to make metals better at certain reactions. They found that adding quinols, which can easily gain or lose electrons, to metal complexes can open up new possibilities. Quinols can help metals tackle tough tasks like breaking down reactive oxygen species (ROS), which can harm our cells. These complexes can work like enzymes in our bodies that deal with ROS. Even metals that usually can't do this job, like zinc, can now help. The structure of the ligand (the part that binds to the metal) plays a big role in how well this works.Sometimes, compounds that aren't great at one job can be really good at another. Quinols can also make some metals better at reducing oxygen, similar to how some enzymes work. They can even change the final product of this reaction. By carefully controlling the environment around the metal, scientists can use common and cheap metals like iron and cobalt to efficiently reduce oxygen. The starting point of the reaction cycle matters, with iron starting as Fe(III) being more efficient so far.