Easing IBS: Can Mice Show Us the Way with Delta Drugs?

Irritable Bowel Syndrome (IBS) is a tough nut to crack, and finding new treatments is a top priority. Scientists have been experimenting with a special type of mouse that mimics human IBS symptoms. This mouse model is called the Chronic Vicarious Social Defeat Stress (cVSDS) model. Coincidentally, there's a type of drug called delta receptor agonists that reduces stress in rodents with hardly any side effects. Scientists wanted to see if these stress-fighting drugs could also help with IBS symptoms in these stressed mice.Why use mice, you wonder? Studying IBS in mice helps us understand the condition better and test potential treatments. Surprisingly, the experiments showed that these delta receptor agonists might do more than just reduce stress—they could also soothe IBS symptoms. However, mice aren't humans, so more research is necessary before we can test these drugs on people.