Exercise Benefits Change with Mouse House Temperature

Scientists are curious about how room temperature affects exercise benefits in mice. They put male mice in two different conditions: room temperature (21°C) and a warmer, comfy temperature (29°C). These mice either exercised for six weeks or did a quick workout. Guess what? Mice in the warmer environment had better glucose control after long-term exercise. However, the exercise didn't shrink their fat cells as much as in the room temperature group. The temperature also played a big role in how certain proteins behaved in the mice's muscles. These proteins help with sugar storage and energy use. Interestingly, some proteins reacted differently depending on whether the mice exercised for a short or long time.Exercise also changed how certain hormones, called exerkines, were produced. These hormones help with metabolism, and their levels depended on the temperature and how long the mice exercised. One hormone, Metrnl, was always higher after long-term exercise, no matter the temperature. But after short workouts, it dropped. These findings show that temperature can really affect how exercise helps mice. Room temperature might not show the full benefits of exercise. So, scientists suggest using a warmer temperature in future experiments to get a better idea of how exercise helps.