Peroxisomes: Little Powerhouses and Their Role in Disease

Peroxisomes are tiny organelles that play a big role in our cells. They help protect us from damage caused by reactive oxygen species (ROS), which are like tiny troublemakers in our bodies. Peroxisomes do jobs like breaking down certain metabolites, making cholesterol, and creating ether phospholipids. Unfortunately, these jobs sometimes produce ROS as byproducts. But don't worry, peroxisomes have their own antioxidant systems to deal with these troublemakers.Sometimes, though, things can go wrong. Peroxisomes can either handle the ROS or let them cause oxidative stress, which can lead to serious diseases like neurodegenerative disorders and even cancer. Scientists have been trying to figure out this relationship for a long time, but they're still not sure exactly how it works. Our review will give you the latest scoop on how peroxisomes' redox system works and how it's connected to these stress-related diseases. It's like solving a big puzzle, piece by piece.