Week 16 NFL Picks: Unexpected Wins and Big Plays
USAFri Dec 19 2025
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Week 16 of the NFL season is here, and it's shaping up to be a wild one. With injuries piling up and playoff spots on the line, there's plenty of drama to go around. Let's break down some of the most intriguing matchups and player props for the week.
The Panthers are riding high after a big win over the Saints, and they'll look to keep the momentum going against the struggling Buccaneers. The Bucs have been a mess lately, and the Panthers seem like the better team right now. Expect a high-scoring game, and the Panthers should come out on top.
The Titans are in a tough spot against the Chiefs, but they might have a chance here. The Chiefs are dealing with injuries and the aftermath of an early playoff exit, and that could take a toll on their performance. The Titans are still fighting for their playoff lives, and they might be able to pull off an upset.
The Giants are another team that could surprise people this week. They're at home against the Vikings, who are coming off a big win over the Cowboys. The Giants haven't been great this year, but they're still a dangerous team, and they might be able to pull off a win here.
As for player props, there are plenty of interesting options to consider. Quinshon Judkins is a solid pick to rush for over 61. 5 yards against the Bills. The Bills' defense has been vulnerable to the run lately, and Judkins should be able to take advantage.
Kenneth Gainwell is another player to keep an eye on. He's been a reliable target for Aaron Rodgers, and he should see plenty of action against the Steelers. Expect him to haul in over 4. 5 receptions.
TreVeyon Henderson is a long shot to rip off a big gain, but he's always a threat to take it to the house. The Patriots' offense has been clicking lately, and Henderson should have plenty of opportunities to make a big play.
When it comes to touchdown scorers, Colston Loveland is a solid bet against the Packers. The Bears are banged up, but Loveland has been coming on strong lately, and he should be able to find the end zone.
Chase Brown is another player to watch. The Bengals are looking to bounce back against the Dolphins, and Brown should be a big part of their game plan. Expect him to find the end zone at least once.
Nico Collins is a bit of a risk, but he's a big-play threat for the Texans. The Raiders' defense has been shaky lately, and Collins should be able to take advantage. He's a solid bet to score at least once.
https://localnews.ai/article/week-16-nfl-picks-unexpected-wins-and-big-plays-9e794e5a
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