Natural Pain Relief: Harnessing Birth Tissue for Post-Surgical Relief

Pain after surgery can be really tough. Opioids, often used for this, have serious side effects and can even be deadly. So, there's a big need for safer, non-opioid treatments. Researchers found that a product made from human amniotic membrane, called Clarix Flo, can reduce this pain in mice without the dangerous side effects of opioids. It works by directly blocking pain signals in certain nerve cells.They also found a key component in this membrane, called HC-HA/PTX3, which they purified for better use. This component alone can do the same job as Clarix Flo in blocking pain. It does this by changing the structure of nerve cells, which stops pain signals from working properly. This discovery is exciting because it shows that natural products from birth tissue can be a great alternative to opioids. Plus, it helps us understand more about how these products actually work to block pain.