SCIENCE
New Gel Boosts Sperm Cell Growth
Tue Jun 17 2025
Scientists have developed a new gel that could change the game for growing sperm cells outside the body. This gel is made from a substance called chitosan, which turns into a gel at body temperature. The gel is then covered with a special mix of proteins and other stuff that sperm cells need to grow. This mix is taken from testicular cells. The result is a gel that helps sperm cells stick and grow better than ever before.
The new gel has a smooth surface and is very friendly to cells. It absorbs water well and can lose weight quickly, which is good for cell growth. Sperm cells grown on this gel are more stretched out and stick to the surface better. This is a big deal because it means the cells are healthier and more likely to grow into sperm.
Tests showed that the genes needed for cell growth were much more active in the new gel. This means the cells are growing faster and healthier. The new gel mimics the natural environment where sperm cells grow in the body. This is a big step forward for scientists trying to create sperm in the lab.
The new gel could be a game-changer for treating infertility. It provides a better environment for sperm cells to grow. This could lead to new treatments for people who have trouble having children. The gel could also help scientists study how sperm cells develop. This could lead to new discoveries about how sperm cells work.
However, there is still a lot of work to be done. Scientists need to do more tests to make sure the gel is safe and effective. They also need to figure out how to use the gel to create sperm in the lab. This could take many years of research. But the new gel is a big step forward in the right direction.
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questions
What are the potential long-term effects of using this hydrogel scaffold on spermatogonia cells?
How does the use of testicular cell-conditioned chitosan thermosensitive hydrogel compare to other existing methods for spermatogonia cell culture?
How does the decellularization process affect the overall efficacy and safety of the hydrogel scaffold?
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