HEALTH

Tackling Tough RA: Links to Obesity and Fibromyalgia

EURSat Jan 04 2025
Trying to manage rheumatoid arthritis (RA) with medications that just don't seem to work. That's the reality for many patients with a form of RA called Difficult-to-Treat RA (D2T-RA). This type of RA can be tough to handle, even with multiple treatments. What's interesting is that obesity and fibromyalgia are both connected to D2T-RA, regardless of the patient's age or gender. So, why does this happen? Well, D2T-RA is a complex issue. Doctors use a set of rules called EULAR criteria to define it. Researchers are still trying to figure out what makes some people more likely to have D2T-RA. It's a bit like a puzzle they're trying to solve. Think about obesity. It's not just about being overweight; it can also affect how your body responds to treatments. Fibromyalgia, on the other hand, is a condition that causes widespread pain and tenderness. Having both of these issues at the same time as RA can make the RA harder to treat. Researchers are working hard to understand these connections better. They hope that by learning more about D2T-RA, they can find new ways to help patients who struggle with this challenging form of RA.

questions

    How significant is the proportion of patients with RA who are classified as having D2T-RA?
    Could there be an undisclosed link between big pharma and the prevalence of D2T-RA?
    What are the specific biological mechanisms that link obesity and fibromyalgia to D2T-RA?

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