SCIENCE

Unlocking The Power of Pseudozyma: The Future of Squalene Production

Sun Apr 27 2025
Pseudozyma is a type of yeast. It has a special talent. It can make squalene. This is a valuable substance. It is used in food, medicine, and cosmetics. It is a big deal in the industry. It is important to find ways to make squalene safely and sustainably. This is where Pseudozyma comes in. It can produce squalene in a way that is good for the environment. Pseudozyma sp. P4-22 is a special type of Pseudozyma. It was created through a process called mutagenesis. This process involves using plasma to change the yeast's DNA. The result is a yeast that can produce more squalene than before. This is a big step forward. It shows that we can use science to improve natural processes. The P4-22 strain can use different types of carbon and nitrogen to make squalene. This is important. It means that we can use different types of waste to make squalene. This is good for the environment. It also makes the process cheaper. The researchers found that the best conditions for growing P4-22 involve using corn steep liquor as a nitrogen source. They also found that the best pH level is 5. 5 and the best sea salt concentration is 5 grams per liter. These conditions help the yeast grow and produce more squalene. This is a big deal. It shows that we can optimize the process to make it more efficient. Under the best conditions, the P4-22 strain can produce 64. 42 grams of biomass and 2. 06 grams of squalene per liter. This is a lot of squalene. It shows that P4-22 has the potential to be used on a large scale. This is important. It means that we can make squalene in a way that is sustainable and good for the environment. It also means that we can make squalene more cheaply. This is good for the industry. It shows that we can use science to solve problems.

questions

    What is the role of sea salt concentration in the medium, and how does it affect the squalene production process?
    What if Pseudozyma sp. P4-22 decided to go on a strike and stopped producing squalene until it got better working conditions?
    How does the pH level of 5.5 impact the growth and squalene production of Pseudozyma sp. P4-22 compared to other pH levels?

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