Week 16 Fantasy Football Showdown: Who to Start and Who to Sit
USAThu Dec 18 2025
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The Week 16 fantasy football matchups are here, and it's time to make some tough decisions. With injuries, holiday plans, and tough matchups, it's not easy to set your lineup. Let's break down some key players and their matchups to help you make the best decisions.
The Los Angeles Rams and Seattle Seahawks are set to face off in a close game. The Seahawks are slight favorites, but the Rams have a strong offense. Puka Nacua and Jaxon Smith-Njigba are must-starts, but other players like Rashid Shaheed and Colby Parkinson are also strong options. The Rams' defense has been tough against quarterbacks, so Sam Darnold may not be a great option. Matthew Stafford could be a QB1, but losing Davante Adams hurts his outlook. The running back situation is a bit murky, with Kyren Williams and Blake Corum splitting carries. Kenneth Walker III and Zach Charbonnet are also in a timeshare, making it hard to predict who will have the better game.
The Philadelphia Eagles and Washington Commanders matchup is another interesting one. Jalen Hurts, Saquon Barkley, and A. J. Brown are must-starts, but DeVonta Smith and Dallas Goedert are also strong options. Terry McLaurin could have a tough time against the Eagles' defense, while Marcus Mariota is a decent QB2 option. The running back situation for the Commanders is unclear, with Chris Rodriguez and Jacory Croskey-Merritt both in the mix. Deebo Samuel could need a touchdown to pay off in fantasy.
The Green Bay Packers and Chicago Bears game is another one to watch. Josh Jacobs is a must-start if he's active, but D'Andre Swift and Kyle Monangai are also strong options. Jayden Reed is a solid flex play, while Jordan Love and Caleb Williams are both decent QB2 options. The Bears' defense has been tough against the pass, so Williams may struggle.
The Buffalo Bills and Cleveland Browns matchup is a bit more one-sided. Josh Allen and James Cook are must-starts, but Quinshon Judkins is also a strong option. Khalil Shakir is a low-ceiling flex play, while Shedeur Sanders is best left on the bench. Jerry Jeudy and Harold Fannin Jr. are also not great options against the Bills' tough defense.
Injuries and matchups can make or break your fantasy team, so it's important to stay up-to-date on the latest news. With the right decisions, you can come out on top in Week 16.
https://localnews.ai/article/week-16-fantasy-football-showdown-who-to-start-and-who-to-sit-4063cc37
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