SPORTS
Week 2 NFL Bets: Smart Picks and Bold Predictions
USA, Las VegasThu Sep 11 2025
Week 1 left bettors scratching their heads, but Week 2 brings new opportunities.
Standout Bets to Consider
Buffalo Bills vs. New York Jets
- Bills heavy favorites, but Jets' offense showed promise in Week 1.
- Jets at home and a full touchdown underdog: Solid bet to cover the spread.
Philadelphia Eagles vs. Kansas City Chiefs
- Eagles' offense struggled in Week 1, but Chiefs' defense has concerns.
- High total points expected: Betting the under might be the way to go.
Los Angeles Rams vs. Tennessee Titans
- Rams dealing with injuries on offensive line.
- Titans' defense held Bo Nix to just 4 yards per attempt in Week 1.
- Titans could be a live underdog.
Carolina Panthers vs. Arizona Cardinals
- Cardinals' run game ranked seventh in EPA per rush in 2024.
- Panthers' defense struggled against the run.
- Cardinals are a solid bet to cover the spread.
Los Angeles Chargers vs. Las Vegas Raiders
- Chargers' offense surprised in Week 1 with a pass-heavy attack.
- Raiders' defense forced Drake Maye into one of his worst games.
- Raiders are a solid bet to cover the spread.
Other Notable Games
Washington Commanders vs. Green Bay Packers
- Packers dealing with injury questions on offensive line.
- Packers are a solid bet to cover the spread.
Jacksonville Jaguars vs. Cincinnati Bengals
- Total points expected are low, but anything under 50 points feels too low.
New York Giants vs. Dallas Cowboys
- Cowboys looked better than expected in Week 1.
- Giants looked worse than expected.
- Cowboys are a solid bet to cover the spread.
Chicago Bears vs. Detroit Lions
- Lions dealing with injuries on offensive line.
- Bears are a solid bet to cover the spread.
New England Patriots vs. Miami Dolphins
- Dolphins' offensive line in disarray.
- This one is a pass.
San Francisco 49ers vs. New Orleans Saints
- 49ers' defense impressed in Week 1.
- 49ers are a solid bet to cover the spread.
Seattle Seahawks vs. Pittsburgh Steelers
- Steelers dealing with injuries on offensive line.
- Seahawks are a solid bet to cover the spread.
Cleveland Browns vs. Baltimore Ravens
- Ravens are heavy favorites.
- Ravens are a solid bet to cover the spread.
Atlanta Falcons vs. Minnesota Vikings
- Vikings' defense is one of the best in the league.
- Vikings are a solid bet to cover the spread.
Denver Broncos vs. Indianapolis Colts
- Colts are dealing with injuries on offensive line.
- Colts are a solid bet to cover the spread.
Tampa Bay Buccaneers vs. Houston Texans
- Texans' defense is one of the best in the league.
- Texans are a solid bet to cover the spread.
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questions
What data supports the idea that the Rams' offense struggles significantly with multiple starting linemen out?
How reliable are the assumptions about the Bills' defense based on a single game performance against the Ravens?
Could the Eagles' offensive struggles be a result of intentional sabotage by the defensive coordinator?
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