HEALTH
Why Thin People Get Fatty Liver Disease
Fri Nov 15 2024
You might think fatty liver disease is only for overweight folks. Surprise! About 20% of people with this condition are actually thin. This isn't just about being obese; it's about how your body handles fat and sugar. When your liver stores too much fat, it's called hepatic steatosis. And even if you're not overweight, you could still have it. Doctors call this lean nonalcoholic fatty liver disease (NAFLD).
Under the microscope, lean NAFLD is split into two groups: lean metabolic-associated fatty liver disease (MAFLD) and cryptogenic steatotic liver disease. You get the lean MAFLD label if you have risk factors like high blood pressure or diabetes. But if you don't have any of those risk factors, welcome to the club of cryptogenic steatotic liver disease.
But wait, there's more! A specific genetic variant, PNPLA3, plays a tricky role. It can make your liver more sensitive to fat and sugar, even if you're not overweight. So, while you might look thin on the outside, your liver could be silently struggling.
This isn't just about looks; it's about your body's internal battle. And understanding it can help you take better care of yourself. So, even if you're thin, don't ignore your liver's health.
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questions
What are the potential limitations of classifying lean NAFLD as either lean MASLD or cryptogenic steatotic liver disease?
How does PNPLA3 affect lean individuals with hepatic steatosis?
Could the new nomenclature be a ploy to make lean people seem more unhealthy?
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