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Nov 22 2024SCIENCE

Unraveling the Mysteries of APP-CHMINACA: A Metabolic Journey

Ever wondered how your body processes synthetic cannabinoids? Let's dive into the fascinating world of APP-CHMINACA, a synthetic cannabinoid that's been making waves. Scientists have been busy figuring out how this substance breaks down in the body. They've done this by mixing it with human cells in

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Nov 22 2024SCIENCE

Cleaning Up Sewage: How Tiny Ceramic Powders Help

Ever wondered how we can make sewage treatment more effective? Scientists have discovered that using tiny ceramic powder carriers in a special treatment bed can really make a difference. They tested this method on simulated sewage overflows, and the results were impressive. The ceramic powders, smal

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Nov 22 2024SCIENCE

USP8: The Unexpected Hero in Endosome Maturation

Endosomes are like tiny sorting centers in our cells, and they need to go through some steps to mature properly. This process is like a relay race, where one runner (Rab5) hands over the baton to another (Rab7). But how this handover happens is a mystery. Meet USP8, a protease that cuts off tiny ta

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Nov 22 2024SCIENCE

Meet ProtPipe: Your Multitool for Proteomics and Peptidomics Data

Mass spectrometry (MS) is like a superhero in the world of science, helping us find and understand proteins. It's key in personalized medicine, systems biology, and biomedical research. But analyzing MS data can be tough. That's where ProtPipe steps in. It's a tool designed to make MS data analysis

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Nov 22 2024SCIENCE

How T-follicular Helper Cells Transform into TR1 Cells

Ever wondered how certain T cells can switch their roles in the body? Let's dive into how T-follicular helper (TFH) cells can transform into T-regulatory type 1 (TR1) cells. These changes happen when the body is continuously exposed to foreign substances, a process known as chronic antigenic stimula

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Nov 22 2024SCIENCE

Brain's Immature Neuroblasts: A New Hope for Regeneration

Deep within the mouse brain, in the subventricular zone, lies a special group of cells called neural stem cells (NSCs). These cells give birth to others called transient-amplifying progenitors (TAPs), which in turn generate neuroblasts (NBs). These cells all play important roles in a process called

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Nov 22 2024SCIENCE

Skies Over America: Measuring Aerosols with High-Flying Instruments

In October and November 2017, NASA and the Netherlands Institute for Space Research (SRON) teamed up for the ACEPOL campaign. This event saw six advanced instruments, including four multi-angle polarimeters (MAPs) and two lidars, fly over the western United States on NASA's ER-2 high-altitude aircra

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Nov 22 2024SCIENCE

Space Telescopes and Starshades: Finding Earth-like Worlds

Imagine going on a cosmic treasure hunt for planets similar to our own. NASA's New Worlds Observer (NWO) mission is an exciting step in this direction. This mission involves a 4-meter space telescope and a 50-meter starshade placed at a stable point between Earth and the Sun, known as L2. The goal?

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Nov 22 2024SCIENCE

Harmonizome 3. 0: A Giant Leap in Understanding Genes and Proteins

You might be wondering what makes the Harmonizome 3. 0 so special. Well, let’s dive into it! This new version of the Harmonizome database has been upgraded to include a whopping 26 new datasets. What does that mean? It means that it now contains nearly 12 million associations between genes and vario

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Nov 22 2024SCIENCE

Can AI Predict Chemical Colors?

Imagine being able to guess a chemical's color just by looking at its structure. That's what scientists did with machine learning! They trained four different models to predict the colors of water-soluble organic compounds. The boosting technique model was particularly useful, helping scientists fig

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