MLH1
Protein-coding gene in humans
Summary
DNA mismatch repair protein Mlh1 or MutL protein homolog 1 is a protein that in humans is encoded by the MLH1 gene located on chromosome 3. The gene is commonly associated with hereditary nonpolyposis colorectal cancer. Orthologs of human MLH1 have also been studied in other organisms including mouse and the budding yeast Saccharomyces cerevisiae.
Originally created by Arcadian
3/5/2007, 7:17:24 PM
Modified
10/31/2025, 9:22:43 PM
Recent revisions
no sentence
Move 2 urls. [[User:GreenC/WaybackMedic_2.5|Wayback Medic 2.5]] per [[WP:URLREQ#nih.gov]]
/* Deficient expression in cancer */ +image
[[MOS:PERCENT]], URL update
Changing [[Wikipedia:Short description|short description]] from "Protein-coding gene in the species Homo sapiens" to "Protein-coding gene in humans"
+[[Category:DNA repair]], [[Category:Mutation]], [[Category:Oncogenes]]
Added doi-access. | [[:en:WP:UCB|Use this bot]]. [[:en:WP:DBUG|Report bugs]]. | Suggested by Headbomb | #UCB_toolbar
/* top */ minor ce
clarified relationship to Lynch (HNPCC)
Alter: doi-access. Add: doi-access. | [[:en:WP:UCB|Use this bot]]. [[:en:WP:DBUG|Report bugs]]. | #UCB_CommandLine
[[Wikipedia:OABOT|Open access bot]]: doi updated in citation with #oabot.
[[Wikipedia:OABOT|Open access bot]]: doi updated in citation with #oabot.
[[Wikipedia:OABOT|Open access bot]]: doi added to citation with #oabot.
Add: s2cid. | [[WP:UCB|Use this bot]]. [[WP:DBUG|Report bugs]]. | Suggested by Whoop whoop pull up | [[Category:Genes on human chromosome]] | #UCB_Category 166/484
link [[astrocytoma]] using [[:en:User:Edward/Find link|Find link]]
[[User:Cewbot/log/20201008/configuration|Fixing broken anchor]]: [[Special:Diff/736751596|2016-08-29]] #Mutation frequencies in cancers→[[Whole genome sequencing#Mutation frequencies]]
what's with all the names?
Importing Wikidata [[Wikipedia:Short description|short description]]: "Protein-coding gene in the species Homo sapiens" ([[Wikipedia:Shortdesc helper|Shortdesc helper]])
/* Role in DNA mismatch repair */
Removed parameters. | [[WP:UCB|Use this bot]]. [[WP:DBUG|Report bugs]]. | Suggested by AManWithNoPlan | #UCB_webform 277/2451
