Have you ever wondered why some cancer cells just refuse to die? One of the culprits is a pathway called PI3K/AKT/mTOR, which helps cancer cells grow and divide. Scientists are working on drugs that can shut down this pathway and stop cancer in its tracks. One promising drug is based on a chemical c
Imagine you can't absorb creatine, a vital nutrient for brain cells. This is a reality for people with a rare disease called creatine transporter deficiency (CTD). But scientists have come up with a clever solution: dodecyl creatine ester (DCE), a special form of creatine that can slip right through
Xylazine, a drug often mixed with opioids, is causing serious health issues in the United States. While it's mainly known for affecting α2-adrenergic receptors, its harmful effects can't be fully reversed by drugs that block these receptors. Scientists have now found that xylazine also targets α7 ni
Ever wished you could see the weather right from your macOS menu bar? With the latest macOS 15. 2 update, old Mac users can now add a Weather widget to their menu bar. This means no more switching to the Desktop to check the weather. Let's see how you can do this and explore some new features. Firs
Imagine you're a doctor trying to treat someone with a serious mental illness, like schizophrenia, bipolar disorder, or major depression. It can be tough, right? Many people don't respond to the first treatment, and that's a problem. A group of scientists and doctors, called the Psych-STRATA consort
When a body is found at a crime scene, figuring out how long it's been there is super important for solving the case. Scientists are looking at tiny bits of genetic material called microRNAs (miRNAs) that stay stable even after death. This study used a special tool called a molecular beacon probe to
Did you know that about 40% of people with HIV face brain problems called neurocognitive impairment (NCI)? This issue can mess up their daily lives, make it tough to stick to their HIV meds, and even shorten their lifespan. Many things can cause NCI in HIV patients, like taking the wrong meds, getti
Inclisiran, a drug designed to reduce lipoprotein cholesterol levels and minimize cardiovascular disease risk, is currently under scrutiny for its adverse effects. Researchers have dived into the FDA's Adverse Event Reporting System to examine real-world data on inclisiran's potential dangers. This
For years, doctors have used single medications to treat high cholesterol and prevent heart disease. But with the arrival of statins, the focus has shifted to using combinations of drugs, both old and new, to better manage cholesterol levels. This approach, called combination therapy, is gaining tra
One of the newer series in the Star Wars universe, The Acolyte, didn’t make it past its first season. The show began with a bang, drawing in 4. 8 million viewers for its premiere and over 11 million around the world within just five days. But as episodes continued, fans seemed divided, which saw a d
