People are talking about weight loss drugs on social media. These drugs, known as GLP-1 RAs, are popular. But what are people saying about them? Are they talking about side effects? Both short-term and long-term ones? What about side effects that happen together? These are important questions. Social media is a big place. It's where people share their experiences. F...
The financial impact of cancer treatments goes far beyond the cost of the drugs themselves. Side effects from these treatments can rack up significant bills, and if these costs are not accurately measured, it can skew the overall assessment of a treatment's value. The extra costs from side effects are often overlooked. These costs can include things like extra h...
Vaccines play a big role in stopping infectious diseases. But they can also cause unwanted side effects. These are called adverse events. Usually, spotting these side effects involves a lot of manual work. This is slow and limited in what it can find. There is a new way to look at these side effects. It uses something called Large Language Models. These models can u...
Cancer is a massive health problem around the world. One major breakthrough in fighting cancer is a type of treatment called immune checkpoint inhibitors. These treatments help the body's immune system fight cancer by blocking certain proteins. These proteins are like brakes on the immune system. By releasing these brakes, the immune system can attack cancer cell...
First, let us understand the big picture. Immunotherapy has transformed the way doctors fight advanced liver cancer. This is great news. However, it is not all sunshine and roses. These treatments can cause serious heart problems. These issues can make the treatment less effective. Doctors call these problems cardiological adverse events or MACE. These can be ...
Loa loa, a parasitic worm, has long been seen as relatively harmless. However, for those with high levels of microfilariae in their blood, taking ivermectin can lead to serious problems. These issues can range from mild to severe, with encephalopathy being a major concern. The current thinking is that problems start when microfilarial densities (MFD) hit 8, 000 per m...
Fluoxetine, a widely used antidepressant, has been under the microscope. Researchers took a deep dive into the FAERS database. This database is a treasure trove of information. It collects reports of side effects from medications used in real-world settings. The goal? To spot any unexpected or harmful reactions from fluoxetine. The FAERS database is a goldmine for un...
In Korea, vaccines are an essential part of public health, but you should sit tight to find out the kick in the cold water. These vaccines are really necessary when it comes to keeping check on babies young and vulnerable. It is no ordinary slope to analyze infant specific reactions to vaccinations. Now, eyes would typically bigger than their bellies fuelled up the c...
COVID-19 vaccines are being used in many countries. People are very careful when it comes to safety. Literally billions of text reports about VAE's are being collected from social media and VAERS. One way to understand what is being said is to use large language models (LLMs) that can understand context but may not perform well in Named Entity Recognition (NER). W...
Have you ever heard of FXa inhibitors? These are medicines that help stop blood clots. But how do they affect kids? A recent study tried to figure this out by looking at what we call "adverse events" or AEs, which are side effects. The researchers did something called a meta-analysis, which is like a big review of many studies. They also did a pharmacovigilance study...