Scientists have been working hard to improve targeted drug delivery by using the acidic environment in tumors. They focus on changing the active sites of drugs, like hydroxyl groups, to enhance stability, lower toxicity, and boost how well the drug hits its target. But the problem lies in making the
Imagine trying to find a tiny needle in a haystack. That's what it's like to detect microRNA-21 (miRNA-21), a key player in cancer. These tiny molecules are hard to spot due to their low numbers. Scientists have come up with a clever way to make this detection easier. They've created a platform usin
The medical world is divided on whether to use Mohs micrographic surgery (MMS) for early-stage melanoma. Some doctors insist on randomized controlled trials (RCTs) to prove MMS is better than the traditional wide local excision. The problem is, there aren't any RCTs yet, but plenty of studies show M
Diabetic wounds can take a very long time to heal, mainly because of bacteria and too much inflammation. Scientists have created a special nano-trap called GC@Pd. This tiny trap has a clever trick: it changes its job based on the wound's condition. When the wound is in the early stage, it's acidic
Did you know nearly 2. 2 billion people globally suffer from vision impairment? That’s a lot of eyes struggling! The eye is like a fortress, protecting itself with barriers that make it tough for medicine to get in. This is especially true for diseases deep inside the eye. Doctors usually use eye dr
Let's talk about Trypanosoma brucei, a sneaky single-celled parasite that's tough to deal with. This tiny bugger doesn't follow the usual DNA commands you'd expect. Instead, scientists uncovered a unique way its genes stay in control: through a fascinating lifecycle of RNA. Imagine RNA as the DJ of
Did you know that many eye diseases show signs in the retina before symptoms appear? That's why scientists are working on ways to detect these diseases early. One new method is called Pan-Ret. It's a special system that can spot abnormalities in retinal images without needing lots of labeled data. H
Ever wondered how the endoplasmic reticulum (ER)—the biggest compartment in our cells—moves things around inside? This is a big deal, especially for understanding diseases that happen when the ER doesn't form right. Scientists think the ER might use tiny muscle-like contractions to move stuff around
Over the past few years, tiny nanoparticles made from special polymers have caught the eye of researchers and doctors for treating cancer. These smart particles can deliver medicine right where it's needed in the body. However, while many amazing ideas have come up in labs, not many have made it to
Imagine if robots could feel and sense the world around them like humans do. That's what scientists have been working on with a new flexible sensor. This sensor is like a tiny, smart patch that can detect pressure, temperature, and even magnetic fields. It's made of a flexible coil on a polyimide ba
