Ever wondered what causes gout, that painful arthritis flare-up? It's all about uric acid, and a crucial enzyme called xanthine oxidase (XO). Picture XO as a little worker in our bodies, responsible for producing uric acid from purines like hypoxanthine and xanthine in the final steps of a process c
In Japan, doctors kept an eye on how well isatuximab plus pomalidomide and dexamethasone (Isa-Pd) worked for people with relapsed or refractory multiple myeloma (RRMM) who were frail. They collected data from patients treated between October 2020 and October 2021, following them for up to a year. Ou
Imagine you're a doctor trying to treat someone with a serious mental illness, like schizophrenia, bipolar disorder, or major depression. It can be tough, right? Many people don't respond to the first treatment, and that's a problem. A group of scientists and doctors, called the Psych-STRATA consort
Everyone's body responds differently to treatments. For people with psoriatic arthritis, switching from one medication to another can sometimes be a tricky business. But what if you could switch straight from one drug to another without any hiccups? That's what researchers found out about a medicati
Julián Castro, who once led US housing efforts, has blasted Donald Trump’s new border enforcement chief, Tom Homan, for his tough stance on migrants. Castro, appearing on MSNBC’s Morning Joe, criticized Homan’s “cruel” approach to handling migrant families. Homan plans to bring back family detention
Myelofibrosis (MF), a type of blood cancer, has seen changes in its treatment over the years. Before the approval of ruxolitinib (RUX), hydroxyurea (HU) was commonly used. The METER study, a large-scale review of patient records from multiple countries, looked into how MF is treated and how healthca
Imagine you're living with HIV and have to take pills every day. Sounds tough, right? Well, there's a newer option: a shot every month or two. But what do people think about this? Researchers asked 30 adults in the US who are currently on HIV treatment. They wanted to know if questions about their f
Imagine traveling back in time to witness Japan's long battle against smallpox. Artwork and woodblock prints tell this tale, capturing the emotions and methods used to fight the disease. Let's start with smallpox's arrival in Japan and the traditional treatments that were tried. These methods might
Warner Bros. has some big changes planned for its upcoming movie releases. One of the most notable adjustments is that Matt Reeves’ upcoming Batman sequel will now premiere on October 1, 2027, instead of October 2, 2026. The reason? Production for this special effects-heavy film won’t start until la
You know how some kids have a slight overbite or underbite? Well, this kid had something much bigger to deal with: a giant open bite due to a large tongue, or what doctors call macroglossia. This isn't very common and makes it tough to bite and chew properly. It also affects the way the face looks.
