Have you ever wondered how different HIV treatments work for older adults? A study took a close look at how well dolutegravir-based regimens stack up against others like raltegravir-, elvitegravir-, bictegravir-, and darunavir-based regimens. This study involved older veterans living with HIV and ai
Femur fractures are a common injury, and fixing them is a big challenge for orthopedic surgeons. Sometimes, after surgery, the bone near the implant can break again. This is called a peri-implant femoral fracture (PIFF). Not many studies have looked into how often this happens, how it's treated, and
Sickle cell disease, a hereditary condition, can cause some tough challenges for men, especially when it comes to priapism. Priapism is a condition where men experience prolonged erections without sexual arousal, and it's more than just uncomfortable—it can lead to significant health issues if not m
A recent study took a close look at how both patients and healthcare professionals think about the care pathways for knee osteoarthritis (KOA) in Slovenia. This country, along with others, has health systems that could be more efficient. The study wanted to fill a gap in research by exploring the op
When it comes to treating chronic obstructive pulmonary disease (COPD), doctors need the most reliable evidence to make the best decisions for their patients. Randomized controlled trials (RCTs) are great for showing how well a treatment works, but they don't always tell us how a new treatment compa
Knee injuries can be nasty, especially when they lead to post-traumatic osteoarthritis (PTOA). Imagine tearing a ligament and then dealing with severe joint damage. Scientists have found that a particular protein, colony stimulating factor 1 receptor (CSF1-R), is a key player in making things worse.
Drug-resistant tuberculosis (DR-TB) is a major health issue worldwide, even with effective medicines available. Starting treatment late for DR-TB can lead to worse health, more resistance to drugs, higher risk of spreading the disease, and poorer treatment results. This study looked into why some DR
You might think that treating opioid use disorder is simple with available meds, right? Wrong! Many people face major hurdles, especially when it comes to money. This research wanted to find out why some people give up on treatment. Turns out, the dosh they need to fork out can be a real pain. It's
Ever heard of myasthenia gravis (MG)? It's a rare disease where your immune system goes a bit haywire and attacks muscles. In the Czech Republic, this disease is more than just an interesting medical fact. It's a reality for some folks, and understanding how they're treated and how much it costs is
Have you ever thought about how lung cancer cells move around and invade other parts of the body? It turns out, there's a protein involved in this tricky process. This protein, called integrin α3β1, acts like a helper, making it easier for lung cancer cells to spread. When scientists reduced the amo
