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Dec 23 2024HEALTH

A Unique Tumor in an Unlikely Place

Meet John, a 60-year-old man who faced a rare health challenge. He was diagnosed with a type of tumor called an extramedullary plasmacytoma. This unusual growth didn't form in the bone marrow like most tumors of its kind. Instead, it showed up in the right lacrimal sac fossa, a small area near the e

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Dec 23 2024HEALTH

Boosting Survival: Who Benefits Most from TNBC Immunotherapy?

Immunotherapy, teamed up with chemotherapy, is giving a big boost to people with advanced, metastatic triple-negative breast cancer (TNBC). This combo helps keep the cancer from spreading for longer than chemotherapy alone. But who's getting the most benefits? That's a question scientists are still

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Dec 23 2024HEALTH

The Unseen Hero: Stearic Acid in Health and Disease

Stearic acid, named after the Greek term for "hard fat, " is no ordinary fatty acid. It's busy helping out in various ways, from boosting energy to sending signals within our cells. Like a versatile worker, stearic acid serves as a fuel and plays a vital role in making other bodily fats and lipids.

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Dec 23 2024HEALTH

New Hope for Advanced Breast Cancer: A Look at ADCs

Metastatic breast cancer is serious business. It's when cancer spreads from the breast to other parts of the body. There are two main types: hormone receptor-positive (HR+) and triple-negative (TN). For a long time, chemotherapy (CT) has been the standard treatment. But now, antibody-drug conjugates

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Dec 22 2024HEALTH

Older Adults with HIV: How Different Treatments Compare

Have you ever wondered how different HIV treatments work for older adults? A study took a close look at how well dolutegravir-based regimens stack up against others like raltegravir-, elvitegravir-, bictegravir-, and darunavir-based regimens. This study involved older veterans living with HIV and ai

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Dec 22 2024HEALTH

Broken Bones After Hip Implants: How Bad is it?

Femur fractures are a common injury, and fixing them is a big challenge for orthopedic surgeons. Sometimes, after surgery, the bone near the implant can break again. This is called a peri-implant femoral fracture (PIFF). Not many studies have looked into how often this happens, how it's treated, and

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Dec 22 2024HEALTH

Sickle Cell and Men: Handling Unwanted Erections

Sickle cell disease, a hereditary condition, can cause some tough challenges for men, especially when it comes to priapism. Priapism is a condition where men experience prolonged erections without sexual arousal, and it's more than just uncomfortable—it can lead to significant health issues if not m

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Dec 22 2024HEALTH

Understanding Views on Knee Osteoarthritis Care in Slovenia

A recent study took a close look at how both patients and healthcare professionals think about the care pathways for knee osteoarthritis (KOA) in Slovenia. This country, along with others, has health systems that could be more efficient. The study wanted to fill a gap in research by exploring the op

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Dec 22 2024HEALTH

Choosing the Best COPD Treatments: A Network Meta-Analysis Guide for Doctors

When it comes to treating chronic obstructive pulmonary disease (COPD), doctors need the most reliable evidence to make the best decisions for their patients. Randomized controlled trials (RCTs) are great for showing how well a treatment works, but they don't always tell us how a new treatment compa

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Dec 22 2024HEALTH

Understanding How Blocking CSF1-R Can Help Heal Knee Injuries

Knee injuries can be nasty, especially when they lead to post-traumatic osteoarthritis (PTOA). Imagine tearing a ligament and then dealing with severe joint damage. Scientists have found that a particular protein, colony stimulating factor 1 receptor (CSF1-R), is a key player in making things worse.

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