Lung cancer is a serious and deadly disease. It comes in different types, with non-small cell lung cancer (NSCLC) being the most common. This type of cancer is tricky to treat, especially in advanced stages. Scientists are now looking closely at genes involved in metabolism, especially those that code for membrane transporter proteins known as solute carriers. One o...
Lung nodules, small growths in the lungs, can be worrying. Doctors often use Low-Dose Computed Tomography (LDCT) to check if a nodule is dangerous. But, LDCT can sometimes cause unnecessary worry by giving false alarms. This leads to extra tests and stress for patients. Scientists are working on better ways to spot lung nodules. They are combining different methods ...
The immune system is like a superhero squad, always on the lookout for invaders like pathogens and cancer cells. It's the adaptive immune system, with its T cells and B cells, that's really good at recognizing and taking out these bad guys. So, knowing exactly how many of these immune cells are around is super important for making sure treatments are spot-on. ...
Imagine a group of cancer cells working together like a well-oiled machine. This is what happens in non-small cell lung cancer. Different types of cells within the tumor communicate and cooperate to make the cancer spread. This teamwork is crucial for the cancer's growth and its ability to resist treatment. Scientists have been curious about how these cells talk to ...
Cancer is a major health problem worldwide, claiming millions of lives each year. There is an urgent need to develop new and effective treatments to combat this disease. One promising area of research involves the use of certain compounds called N-heterocycles, with pyrazines being a notable example. These compounds are often found in the structure of many anticancer...
Breast cancer is a global health challenge that scientists are tackling head-on. Instead of just using traditional methods, they are now exploring new ways to fight this disease. One promising approach involves using drugs that target specific proteins called CDK4 and CDK6. These drugs, known as CDK4/6 inhibitors, work by slowing down cancer growth. They make cancer ...
Copper, a metal we often think of as a material for coins or wires, is now being studied for its role in cancer. Researchers have found that copper can help control how cells die in breast cancer. This process is called cuproptosis. Scientists have been looking into how copper-related genes (CRGs) work in breast cancer. They used data from large groups of patients to...
Pleural mesothelioma (PM) is a tough cancer to treat. It's caused by asbestos exposure, and it's not easy to cure. Doctors have been looking for better ways to fight this disease. Recently, they have found some promising results with immune checkpoint inhibitors (ICIs). ICIs are a type of drug that helps the body's immune system recognize and attack cancer cells. ...
'Breast cancer research is always working to improve. Researchers have come up with a cutting edge system. Simulations using polarized Monte Carlo methods enhance the clarity of tissue structures. ' 'Experiments run aimed at detecting tumours at the edges where you'd guess thick slices of the tissue might show problems post surgery. 'The simulation software used giv...
Colorectal cancer is a tricky enemy, with mutations in proteins like APC and AXIN boosting the Wnt/β-catenin pathway. The Wnt/β-catenin pathway is a key player in tumor growth and spreading. The pathway can be turned on in an unwanted way, leading to a buildup of β-catenin. This buildup is caused by problems with a process called ubiquitination, which usually keeps β...