Ovarian cancer is a major health concern for women, with a high fatality rate. Traditional treatments like surgery and chemotherapy often fall short due to drug resistance. This has pushed researchers to explore innovative methods, such as nanotechnology, to fight this disease more effectively. Gold nanoparticles have shown promise in targeting and treating cancer. ...
Cancer treatment is a tough battle, but scientists have found a way to make it easier. They created a new tool called MA@E, which is a special kind of liposome. Liposomes are tiny bubbles that can carry medicines inside them. These liposomes are super stable and can carry two powerful weapons: gold nanorods and Mn-MIL-100. This combo can target cancer cells and kill ...
Imagine tiny molecules that can seek and destroy cancer cells. Scientists have created a special molecule called TPBBT. This molecule has a unique structure that allows it to absorb near-infrared light. This is important because near-infrared light can penetrate deep into the body, making it perfect for targeting tumors. TPBBT has a special trick. It can cha...
Imagine a tiny protein called MALT1. It's like a key player in a game of cancer survival. This protein is part of a group of enzymes called cysteine proteases. It's unique because it's the only paracaspase in humans. This means it has a special role in helping certain types of cancer cells stay alive and grow. These cancers are driven by a pathway called NF-κB. Two t...
Cancer treatment is getting a high-tech upgrade. Scientists are exploring a unique way to fight cancer cells using tiny magnetic particles. These particles, called magnetic nanoparticles (MNPs), are designed to target and kill cancer cells through a process called ferroptosis. Ferroptosis is a special kind of cell death that happens when cells can't handle too much i...
Radiotherapy, a common cancer treatment, often struggles to effectively kill tumor cells. Researchers have discovered a unique way to enhance this therapy using a clever combination of bacteria and a metal called selenium. They've created tiny particles, called BL@SeNPs, which are made by coating the probiotic bacterium Bifidobacterium longum (BL) with selenium nanop...
You might have heard of ginsenoside Rh2, a compound with amazing health benefits. It can help fight certain cancers, reduce inflammation, and even tackle diabetes. But how do we make more of this wonder substance? Scientists have been looking into an enzyme called UGT51 from yeast, which plays a key role in making ginsenoside Rh2. The problem? This enzyme isn't very ...
Copper, a vital trace element in our bodies, plays a key role in energy production and cell repairs. But when copper levels aren't balanced, it can wreak havoc. It triggers oxidative stress and disrupts the energy factories in our cells, leading to severe damage and even cell death. Scientists recently named this type of cell death "Cuproptosis. " It occurs when copp...
Tumors are tricky because they don't all look the same. This makes it tough to hit them with the right medicine. But scientists have found a clever way to use inflammation to guide special cells called neutrophils, which carry drugs, right to the tumor site. They do this by causing a tiny, controlled inflammation in the tumor using something called lipopolysaccharide...
Imagine trying to fight a bad guy (like cancer) but not having enough soldiers (immune cells) to help. That’s where interferon gamma (IFNγ) comes in. This tiny protein wakes up immune cells so they can fight invaders or even cancer cells. Scientists wanted to make a super vaccine for colon cancer, so they played with some cellular genetics. They took CT26 colon canc...