Polymyalgia rheumatica is a condition that causes muscle pain and stiffness. It often affects older adults. Corticosteroids are usually the go-to treatment. But what happens when they don't work or cause too many side effects? That's where sarilumab comes in. It's a medication that's been approved f
Acupuncture is becoming more popular in medical research. But how do we measure its success? One key way is by asking patients about their experiences. These are known as patient-reported outcomes (PROs). However, in mainland China, no one has thoroughly examined how these PROs are utilized in acupu
In the world of healthcare, understanding acute heart failure (AHF) is a tough nut to crack. Why? Because lots of important details are tucked away in unstructured text, not neat little boxes in electronic health records (EHRs). This is where large language models (LLMs) come into play. They can aut
Cancer is a major health issue worldwide, causing many deaths and illnesses. Even with progress in treatment, there are still big hurdles to overcome. This is why scientists are always looking for new ways to fight cancer. One exciting area of research is m5C RNA methylation. This process involv
Mid-Portion Achilles Tendinopathy is a common issue among athletes and active individuals. It is a condition that affects the mid-section of the Achilles tendon, causing pain, stiffness, and a decrease in muscle strength. This problem can be quite frustrating for those who enjoy physical activities.
COPD, or chronic obstructive pulmonary disease, is a long-term lung condition that makes breathing difficult. It is well-known that iron plays a role in how COPD affects the body. This is because of a process called ferroptosis, a type of cell death that depends on iron. Several molecules are involv
Two treatments, sotorasib and adagrasib, have received approval in the USA and Europe for tackling advanced or metastatic non-small cell lung cancer. This type of cancer is marked by a specific mutation known as KRAS G12C. Since these treatments have not been directly compared in clinical trials, re
Fibroids are a common issue for many women. They can cause discomfort and affect daily life. A recent study looked into whether lifestyle changes could help manage fibroids better. The focus was on a program called LIFE. This program combined diet, exercise, and supplements to see if it could improv
The way clinical trials are conducted is changing. More and more, the focus is on making them easier for patients to take part in. This shift is happening because of something called decentralized clinical trials or DCTs. These trials use modern technology to bring the clinical trial experience to t
Bile duct cancers are a tough bunch to beat. They are tricky because they come in different forms and are hard to treat. For a long time, doctors have used a combo of gemcitabine and cisplatin to help patients feel better, even if it couldn't cure them. This was the go-to treatment for over ten year
