Do you know what living in tropical countries could lead to? You might get melioidosis, an infection caused by the bacterium Burkholderia pseudomallei. This tiny bug loves soil and water, making it a common problem in hot regions like Kerala, India. Melioidosis can be mild or severe, depending on ho
In Sri Lanka, many people accidentally or intentionally consume profenofos, an insecticide, and often mix it with alcohol. This makes treating their poisoning much harder. Doctors want to know how alcohol levels in the blood affect the poisoning and how the body processes profenofos. They're trying
Optometrists have always played a crucial role in meeting the challenges and opportunities in eye care. The roots of optometry in the UK reach back to 1629 when Charles I granted a Royal Charter to the Worshipful Company of Spectacle Makers, creating the 60th Livery Company of the City of London. Ho
Digital biomarkers are becoming more common in healthcare, helping doctors make better decisions. Speech is a complex process that involves breathing, voice production, mouth movements, and the way sounds echo. These processes depend on specific brain and body systems. When something goes wrong, it
Didemnins, a family of molecules found in marine creatures, are known for their powerful cancer-fighting abilities. One of the most studied members, Didemnin B, has shown great promise in stopping tumors from growing. But using it in patients has been tough due to problems like poor absorption and h
Imagine you're running a clinical trial to test a new treatment in critical care. You're tracking how patients do after the treatment, but what if some patients don't make it long enough to see the full results? That's what we're calling "truncation due to death. " The big question is, how do we han
Imagine if doctors could see beyond the symptoms and truly understand what makes you, you. That's the idea behind whole person health assessments. Instead of just focusing on diseases, these assessments look at the whole picture: your body and mind, your relationships, your living environment, your
For a long time, doctors have relied on finding physical damage to understand and treat pain. But chronic pain is different. It often doesn't show up on scans or tests, and it's a personal experience that no one else can feel. This makes it tough for doctors to talk about with their patients. This p
Every year, over 60 million people face traumatic brain injuries (TBIs), leading to significant health issues and even death. Managing these injuries is tough, with a heavy toll on individuals and society. For the past couple of decades, there's been a rise in clinical trials focusing on neurocriti
Imagine you're battling advanced biliary tract cancer (ABTC), and your doctors suggest a mix of drugs: nivolumab, modified gemcitabine, and S-1. This combo showed promise in a past trial, but PD-L1 levels didn't tell us much about how well it would work. So, scientists looked at another marker, LAG-
