Bile duct cancers are a tough bunch to beat. They are tricky because they come in different forms and are hard to treat. For a long time, doctors have used a combo of gemcitabine and cisplatin to help patients feel better, even if it couldn't cure them. This was the go-to treatment for over ten years. But now, things are changing. Two big studies, TOPAZ-1 and KEYNOTE...
A recent study has shed light on the potential benefits of arimoclomol for individuals with Niemann-Pick disease type C (NPC). This study, known as NPC-002, was a 12-month trial. It was designed to be double-blind and randomized, with a placebo group for comparison. The main goal was to see how arimoclomol affected the progression of NPC. The results were measured us...
A new method of treating a type of eye cancer is being tested. This cancer is called choroidal malignant melanoma. It grows in the eye's choroid layer. The treatment uses carbon-ion radiotherapy with a rotating beam. This approach was started in March 2018 at a hospital in Japan. The goal was to see if this method is safe and effective. The team looked for patients ...
Hypertension is a sneaky health issue. It often goes unnoticed, but it can cause serious problems if left untreated. For some people, managing high blood pressure is a constant battle. Traditional treatments don't always cut it. This is where a new player, zilebesiran, steps into the ring. It's not your typical medication. Zilebesiran is an experimental RNA interfere...
Asciminib is a drug that has been making waves in the treatment of chronic myeloid leukemia (CML). The ASC4FIRST study is a phase III trial that compared asciminib with other tyrosine kinase inhibitors (TKIs) chosen by doctors. The results were impressive, showing that asciminib was more effective and had better safety and tolerability. This trial included a subgr...
The TOPAZ-1 trial, a major study, has been tracking the effects of a combination treatment on patients with advanced bile duct cancer. This treatment pairs durvalumab with a mix of gemcitabine and cisplatin. The initial results were promising, showing that this combo could extend the lives of those battling this tough disease. The study has now shared more details. ...
Follicular lymphoma (FL) is a significant health issue in Japan, the United States, and Western Europe. It stands as the second most frequent type of non-Hodgkin lymphoma (NHL). Parsaclisib is a drug that targets a specific pathway in cancer cells. It has shown promise in earlier tests with patients who had relapsed or refractory (R/R) B-cell NHL, including FL. The ...
A recent study pitted two popular weight loss drugs against each other. The results showed that Zepbound, made by Eli Lilly, helped people shed nearly 50% more weight than those using Wegovy, from Novo Nordisk. This was the first time these two blockbuster medications faced off in a clinical trial. The study, funded by Eli Lilly, was published in a medical journal. ...
Skin tags, those small, benign growths, often pop up in spots where skin rubs together, like the neck or underarms. While they're usually harmless, they can be a nuisance or even painful if they get twisted or cut off. Doctors have tried various methods to remove them, including freezing or burning them off, but these can leave scars or light patches. Lasers seemed l...
Lung cancer is a serious issue, and small-cell lung cancer (SCLC) is one of the trickier types. It often spreads quickly, making it hard to treat. Doctors have been looking for better ways to fight it. One approach is to use a mix of drugs that work together to attack the cancer from different angles. This is where carboplatin, etoposide, atezolizumab, and bevaci...