The fat around the heart, called epicardial adipose tissue (EAT), is special. It has traits similar to brown fat, which helps burn energy. One important protein in EAT is UCP1, which plays a role in how cells make and use energy. Scientists wanted to see how stopping UCP1 affects the way EAT works, especially in people with type 2 diabetes or heart disease. First, t...
Researchers dug into how certain markers in the blood might hint at heart trouble. They focused on two things: ferritin and glutathione peroxidase 4 (Gpx4), which are tied to a process called ferroptosis. This process is linked to cell damage and death. The study looked at 396 people with coronary artery disease (CAD) who had a procedure called PCI. They also had a ...
Heart issues can be tricky to pinpoint, especially for those with mild to moderate chest pain. Doctors often use stress echocardiography (SE), but it is not always the best tool. It can be a bit of a hassle and often shows normal results even when there is a problem. This is where advanced electrocardiography (A-ECG) comes in. It is a newer method that might change t...
Heart disease is a major issue in the Amazon region of Brazil. It is known that inflammation plays a big role in heart disease. This is why scientists looked into the link between heart disease and infections from Chlamydia pneumoniae and Chlamydia trachomatis. They also studied how the body's immune response, through cytokines, might be involved. The study focused ...
You've probably heard that sudden high blood sugar levels can be bad news, especially for people with heart problems. This is called stress hyperglycemia, and it's been linked to bad short-term outcomes in people with heart issues. But what about the long term? Does stress hyperglycemia also affect people years down the line? And does it matter if you have kidney pro...
You know that smoking isn't great for your heart health. But did you know it might be even more dangerous for people who've already had heart trouble? Let's break it down. Smoking is bad news for anyone's heart. It can cause sudden cardiac death (SCD), which is when your heart suddenly stops beating. But what about people who've already had problems with their heart...
Coronary artery disease (CAD) is a severe health problem worldwide, causing significant harm and death. While factors like oxidative stress, poor lipid management, and bad lifestyle choices are well-known contributors to CAD, recent studies show that immune responses and inflammation also play a role. Malnutrition, which can be changed, has a big impact on how CAD tu...
Percutaneous coronary intervention (PCI), commonly known as an angioplasty, is a go-to treatment for people with severe blockages in their coronary arteries. While this procedure works wonders in the target vessels, it's important to keep an eye on what's happening elsewhere. You see, even after the PCI, the fatty buildup, or plaque, in other parts of the vessels can...