Trichinosis is a serious health issue that affects both humans and animals. Unfortunately, current treatments often face problems like resistance and poor absorption in the body. This means scientists are always looking for better ways to fight this parasite. One approach is to improve how well drugs work by using new methods. A recent study focused on using ivermec...
Asciminib is a drug that has been making waves in the treatment of chronic myeloid leukemia (CML). The ASC4FIRST study is a phase III trial that compared asciminib with other tyrosine kinase inhibitors (TKIs) chosen by doctors. The results were impressive, showing that asciminib was more effective and had better safety and tolerability. This trial included a subgr...
Thermogels are a hot topic in the world of medicine. They are special gels that change shape when heated. This makes them perfect for delivering drugs in a controlled way. The big deal about thermogels is that they can be injected. This means no more scary needles or pills that taste bad. Plus, they are safe for the body and can release medicine exactly where it is n...
Psoriasis is a tough skin condition. It can be really hard to deal with. It can be mild or severe. It can be a real pain. There are two treatments that are quite popular in Italy. They are risankizumab and secukinumab. Both are known to be effective. They help a lot of people. But which one is better? It depends on what you look at. Let's dive in. First, l...
Imagine a young girl in North India facing a tough battle. She has a rare genetic condition called homozygous familial hypercholesterolemia, or HoFH. This means her body can't process cholesterol properly, leading to very high levels of LDL-C, the "bad" cholesterol. This can cause serious health problems and even early death. HoFH is not something that can b...
Imagine living with constant knee or hip pain. That's the reality for many people with osteoarthritis (OA). This condition is a major cause of discomfort and limited mobility. Recently, a new drug called fasinumab has been tested to see if it can help. Fasinumab is a nerve growth factor inhibitor, which means it targets the body's pain signals. The goal of the study ...
Scientists sought to improve the way medicine, like methotrexate, passes through human skin. They used tiny needles called Dr. Pen microneedles and tiny, biodegradable beads called poly(d, l-lactide-co-glycolide) acid microparticles. These beads came in eight different forms. The team studied the beads closely, looking at their size, charge, shape, and how well they ...