In the world of medicine, liver damage from drugs is a big deal. It happens when medicines or their byproducts cause harm. This type of damage is linked to something called oxidative stress. To fight this, the body uses sulfhydryl groups. These are like tiny warriors that protect cells from damage. So, keeping an eye on these groups is crucial for understanding and t...

Drug testing is a complex process. Sometimes, during trials, a drug may cause liver injury. This is a serious issue. The decision to give the drug again, known as a rechallenge, is tricky. There are no clear rules or guidelines to follow. This makes it hard for drug developers and experts to make informed choices. Most of the information available focuses on cases w...

Liver problems caused by drugs are a big deal. They can lead to sudden liver failure, and they often show up only after a long time of taking the drug. This is a huge problem for people who make new drugs. They have to stop their work because it's too risky. But there is new hope. Scientists are using advanced liver models and AI. These two things combined can pred...

Liver damage caused by drugs, known as drug-induced liver injury (DILI), is a serious issue. Doctors often miss the early signs. Here’s where a tiny detail in liver cells comes into play: their mitochondria. When these tiny powerhouses get hurt, they become thicker or stickier, a change we can see as increased viscosity. Scientists have created a special tool named W...