A dangerous fungus, Candida auris, is causing alarm as it spreads across the United States and beyond. This fungus, often called a "superbug, " is becoming more resistant to treatments and is particularly harmful to those already sick or with weak immune systems. The fungus was first found in 2009
Fungi are wily opponents. They can alter their form to evade the effects of medications. Scientists chose two familiar fungi, Aspergillus fumigatus and Candida albicans, to observe their reactions to two common antifungal drugs: AmBisome and Caspofungin. AmBisome is quick. It halts fungal growth ra
Bacteria are sneaky. They find ways to survive even when we throw powerful medicines at them. One of the trickiest is Staphylococcus aureus, especially the kind that doesn't respond to many drugs, like MRSA. Scientists have been working hard to find new ways to beat these tough bacteria. They creat
Proteins are like tiny workers in our body, and they often need a bit of a tweak to do their jobs right. One such tweak is called SUMOylation. It's like adding a small tag to a protein, which can change how it works, where it hangs out in the cell, or even how long it sticks around. This tagging pr
Cancer is a tricky foe, always finding ways to dodge treatments. One type, Ewing sarcoma, often affects young people. It's caused by a gene fusion called EWS::FLI1. This fusion acts like a commander, driving cancer cells to multiply uncontrollably. Scientists made a surprising find. EWS::FLI1 disru
Parasitic worms, or nematodes, cause a lot of trouble. They bring on various diseases in animals and even in humans. The drugs used to fight these pests, known as anthelmintics, are becoming less effective. This is due to the worms developing resistance to these treatments. So, finding new ways to t
Axl is a key player in the TAM family of receptor tyrosine kinases. It plays a significant role in promoting cancer growth and immune system evasion. It also contributes to resistance against various cancer treatments. This makes Axl a hot target for new cancer therapies. Axl's role in cancer is c
Lactate is not just a waste product from sugar breakdown. It is a key player in cancer's strategy. It fuels cells, sends signals, and helps cancer cells talk to each other. This is a big shift from the old idea of lactate. It shows that lactate can move around and affect different cells, tissues, an
Melanoma, a type of skin cancer, often becomes resistant to treatment. This resistance can be due to chemotherapy-induced senescence. This means that instead of dying, some cancer cells stop growing but do not die. This can lead to treatment failure. Finding and targeting these senescent cells is a
Gonorrhea, a common sexually transmitted infection, is a growing concern. It is becoming increasingly resistant to treatment. The ability to monitor this trend in the United States has just been halted. This is due to the recent layoffs of 77 scientists. These experts were responsible for collec
