Imagine a world where antibiotics can't keep up with the bugs they're designed to fight. That's the challenge posed by carbapenemase-producing Enterobacterales (CPEs), a group of multidrug-resistant pathogens that are becoming increasingly hard to treat. These bacteria have plasmids, which are like
Prostate cancer (PCa) often becomes resistant to treatment, making it hard to cure. This type of cancer is linked to unusual lipid metabolism, which makes it tough to treat. Scientists have come up with a clever way to tackle this problem. They designed a tiny nanomachine called HA@CD36i-TR@siSCD1.
Ever thought that the humble cockroach could help fight superbugs? Well, it's true! Scientists are exploring the gut microbiome of Blattella germanica to find new antimicrobial peptides (AMPs). These aren't your typical antibiotics; they're naturally occurring peptides that could be a game-changer i
Malaria has been a relentless enemy in Africa, but the fight against it has become even tougher with the rise of drug-resistant strains. Imagine trying to fix a leaky pipe with a broken wrench—that's what it feels like when antimalarial drugs don't work as they should. Why is this happening? Well, m
Imagine a tiny molecule called HSD52 that helps cancer cells dodge the effects of a common chemotherapy drug, temozolomide. This RNA molecule connects two proteins, NONO and SFPQ, to form a powerful team inside cells. Their mission? To help cancer cells repair damaged DNA faster, making them resista
Cancer is a major health issue worldwide, and breast cancer, in particular, is a significant concern. Despite advancements in treatment and prevention, it remains the second leading cause of cancer-related deaths. Both genetic and environmental factors contribute to the development of breast cancer.
Malaria during pregnancy can be dangerous. But with growing resistance to common treatments, new solutions are needed. One promising drug is dihydroartemisinin-piperaquine (DP), which requires taking for several days. Yet, even simple, single-dose treatments often miss the mark. This issue leaves ex
Shigella infections are becoming harder to treat, especially in places like Bangladesh where people often prescribe their own antibiotics. Scientists have discovered that many Shigella germs are now resistant to multiple drugs, and some can even fight off several types of medicines at once. How do t
Imagine mixing two powerful substances to create a superhero drug against a dangerous disease. That's what scientists have done by combining eugenol and benznidazole to fight Chagas disease. This illness, caused by the protozoan Trypanosoma cruzi, has only two treatment options—benznidazole and nifu
Ever wondered how your body might react to a medicine before you take it? That's where personalized medicine comes in. By combining pharmacogenomics (studying how your genes affect your response to drugs) with nanotechnology, scientists are creating something called nano-enabled pharmacogenomics. Th
