Japan is determined to speed up the availability of new cancer treatments. These treatments offer better outcomes than existing options. To make this happen, countries use special pathways to quicken the approval process. This is known as expedited approval. A study compared the speed of drug approvals in Japan and the United States. It focused on 55 cancer drug...

Cannabis is known for its main active ingredient, Δ9-Tetrahydrocannabinol (Δ9-THC). This compound is the primary psychoactive substance in cannabis. When it comes to legal or workplace issues, measuring Δ9-THC in blood is crucial. Typically, blood is drawn by a trained professional in a medical setting. However, this method can be slow and inconvenient. There is a gr...

Imagine trying to figure out how a drug will behave in a human body. It's a tough job, right? Scientists often use lab tests and animal models to predict this, but these methods aren't always accurate, especially when it comes to drugs processed by an enzyme called uridine diphosphate-glucuronosyltransferase (UGT). This is where humanized mice, specifically hu-PXB mi...

Heart troubles are a big deal around the world, causing lots of harm. Doctors and scientists have been studying hearts using animals and cells in dishes, but these methods don't always work well. The heart is super complex, and it doesn't act alone in the body. This is where multi-organ chips come in, cool new tools that let you see how different organs cha...

The 17th edition of the annual banned-substance review just came out, and it's all about the latest findings in human sports drug testing. This one covers research published between October 2023 and September 2024. Just like before, the focus is on new ways to detect doping and figure out how certain substances work in the body. This year, they've looked into some we...