Dec 20 2024SCIENCE
The Surprising Role of Start Nucleotides in mRNA Immunity
Imagine you're cooking up mRNA in a lab, using a common technique called in vitro transcription (IVT). This method is a big deal for making mRNA therapies and understanding RNA biology. Here's an interesting fact: the mRNA you produce can start with either a 5'-pppG or a 5'-pppA. No big deal, right?
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