Let's dive into the effectiveness of Enfortumab Vedotin (EV) in tackling advanced urothelial carcinoma (a severe form of bladder cancer) in the real world. EV is a unique drug that combines two powerful actions: it targets the nectin-4 protein found in cancer cells and disrupts their structure by in
Stomach and pancreas neuroendocrine tumors are quite the puzzle for doctors. They're not common and often go unnoticed until it's too late, making them difficult to tackle. When these tumors spread, doctors typically start with platinum-based chemotherapy. But here's where it gets confusing. After t
Scientists are excited about narrowband fluorescent emitters for making super-clear organic light-emitting diode (OLED) displays. They've found a new way to make these green light emitters better. The key is a special molecule design, known as the centrosymmetric dianilido-bipyridine boron difluorid
Imagine tiny organisms that live on and inside your body. These are called microbes. During COVID-19, researchers found that these microbes can either help or harm you. The disease caused by the SARS-CoV-2 virus can disrupt the balance of these microbes, making the disease worse. Changes in these m
Gram-positive bacteria, like Staphylococcus aureus, Streptococcus, and Enterococcus, are commonly behind bloodstream infections and heart inflammations. "Complicated bacteremia" is a term doctors use for S. aureus infections that spread to other parts of the body. This requires longer treatment and
Ever thought about how algae can influence shrimp? A fascinating study looked into this by focusing on Litopenaeus vannamei, a common shrimp species. Researchers examined how adding a specific algae, Haematococcus pluvialis, to shrimp food affects their growth, immune system, and gut bacteria at dif
In tropical countries like Thailand, dengue is a big health problem. Kids aged 5-14 get it the most. This study looked into how often kids with dengue get stomach problems and what signs might mean a severe case. Researchers checked medical records of kids aged 0-14 who went to Charoenkrung Prachara
Ever wondered how our minds estimate our memory strength? Researchers took a closer look at this with a study on anchoring information. They had two main ideas: the "glass half full/empty" view, where anchors change how sure we feel about our memory, and the "scale shift" view, where anchors mess up
Ever wondered if having food allergies could affect your ability to conceive? A recent study in North America explored this question. The researchers looked into how self-reported food allergies might correlate with fecundability, which is the likelihood of getting pregnant each menstrual cycle. Th
Rituximab, a drug being tested for its potential in treating systemic sclerosis-associated interstitial lung disease (SSc-ILD), doesn't have the same effect on every patient. Scientists looked into why this is by examining data from the DESIRES trial and using machine learning. They found that the s
