A recent discovery has shed light on a new way to tackle diseases linked to a process called ferroptosis. This process involves the death of cells due to iron overload and oxidative stress. Scientists have found a compound, known as 428, which might hold the key to fighting these diseases. 428 is a modified version of a substance called noscapine. It contains seleniu...
Cigarette smoke from heat-not-burn products, which are marketed as safer alternatives, can still harm the body. This is because they contain chemicals that can damage cells in the blood vessels. These chemicals are called alpha, beta-unsaturated carbonyl compounds. They are found in the smoke of these products. These compounds can cause a specific type of cell de...
Macrophages are like the body's cleanup crew. They rush to the scene of a stroke to help. But sometimes, they make things worse. They release tiny bubbles called exosomes that can mess with the brain's blood vessels. This is part of what happens in a condition called cerebral ischemia-reperfusion injury, or CIRI. It's like when you twist a hose and then let go. The w...
Preeclampsia (PE) is a serious issue during pregnancy. It's tough to spot early and even tougher to treat. Recently, scientists have been looking into something called ferroptosis. This is a type of cell death that needs iron to happen. Researchers think it might play a big role in what causes PE. So, they decided to dig deeper into genes related to ferroptosis in PE...
Brain bleeds, or intracerebral hemorrhages, are a severe type of stroke. They happen when a blood vessel bursts in the brain, causing bleeding. This type of stroke is serious and getting more common worldwide. Doctors don't have a perfect cure yet. Cinnamon might help with brain bleeds. Cinnamon contains a compound called cinnamaldehyde. It has anti-inflammatory, an...
Cancer treatment is getting a high-tech upgrade. Scientists are exploring a unique way to fight cancer cells using tiny magnetic particles. These particles, called magnetic nanoparticles (MNPs), are designed to target and kill cancer cells through a process called ferroptosis. Ferroptosis is a special kind of cell death that happens when cells can't handle too much i...
First, let's talk about the tumor microenvironment, or TME. It's a tough place for treatments to work. Hypoxia, or low oxygen levels, and high levels of glutathione (GSH) make it hard for photodynamic therapy (PDT) to do its job. Scientists have been working on a way to turn these challenges into advantages. They created a new molecule called Ir-Fc. This molecule is ...
Ferroptosis is the new buzzword in lung cancer research. Researchers are diving deep into this cell death process to see how it might help fight cancer. They are using a method called bibliometric analysis to track how research on ferroptosis has changed over time. This isn't just about looking at old studies; it's about finding new trends and hot topics. By doing th...
Our bones might feel far stronger than what they may really be; Rust-like things called reactive oxygen species(Ways to describe them can vary. We've heard of free radicals as an example) could possibly damage them over long stretches of time. This science term for "arthritic degeneration. “ In a fresh twist on an ageing problem. During several tests done on cell c...
Alzheimer's disease (AD) can be quite tricky, with various processes happening behind the scenes in our brains. One of these is ferroptosis, a type of cell death involving iron and oxidative stress. As we age, our body's antioxidant systems may not work as well, leading to more ferroptosis. This can make AD symptoms worse. A key player here is Nrf2, a protein that h...