Lesch-Nyhan syndrome (LNS) is a tough condition to deal with. It's caused by a problem with the HPRT1 gene, leading to high uric acid levels and serious brain issues, like self-harm. Usually, doctors try to fix this with stem cell transplants, but it's not always successful. In this case, a baby wa
Blood-making stem cells are like tiny superheroes. They can grow and turn into different types of blood cells. Scientists want to grow these cells outside the body for treatments and research. They use a special substance called human platelet lysate (HPL) to help these cells grow. HPL is packed wi
Bone marrow transplants can be a lifesaver for people with blood cancers. But they come with some tough side effects. One big problem is severe mouth sores, which can make eating painful and slow down recovery. A recent study looked at how bad mouth sores affect patients' strength and overall feel a
Cancer patients often face a tough journey. Allogeneic hematopoietic stem cell transplantation is a common treatment for blood cancers. It can be very effective. However, it comes with serious side effects. These can include both physical and mental struggles. This can make the recovery process even
Blood cancers are serious business. They often need strong treatments, like hematopoietic stem cell transplantation (HSCT). This procedure can be a game-changer, but it's tough on the body. Patients usually go through intense therapy before HSCT. This can lead to weight loss, muscle loss, or e
Acute myeloid leukemia (AML) is a tough nut to crack. Even with intense chemotherapy, many patients face a high risk of relapse. Things get even worse for those whose leukemia returns or doesn't respond to treatment. But there's a glimmer of hope with a new combo treatment. Researchers look
Doctors and nurses who care for patients undergoing cell transplants have an enormous task. They need to discuss life-threatening situations with their patients and families. But how do these professionals approach these delicate conversations? This study explored the different ways doctors and nur
Imagine a messed-up blood system where blood cells aren't even given a fair chance to grow and do their job. It's called MDS, and it's a problem no one wants. Think of a bunch of key players in the bone marrow. There are special cells called MSCs, which are like the mega landlords of the bone marrow
Stem cell transplants, or HCT, offer hope to those fighting blood cancers. However, the intense treatment makes patients vulnerable to infections. These infections, known as HAI, are a big concern. One way to prevent them is through daily baths with a special soap called chlorhexidine gluconate, or
