Scientists use a method called hydrogen/deuterium exchange mass spectrometry to study how proteins fold. When comparing two drug versions, they need a test that shows the samples are almost identical, not just different. A new approach called TOST uses two one‑sided tests to set limits of acce
The world is running out of important minerals. Smelting these metals also adds a lot of carbon to the air and pollutes water. People need new ways to make materials that are good, cheap, easy to recycle and safe for the planet. Designing such materials is hard because many goals must be met at o
A man from Spring, Texas faces state charges for an attempt to kill OpenAI chief Sam Altman by hurling a Molotov cocktail at his San Francisco house. The defendant, Daniel Moreno‑Gama, appeared in court on Tuesday for the first time. A judge ordered him to be held without bail and set his arraignmen
Ten years after a Fairfax County firefighter was found in Shenandoah National Park, her family sees a small but significant shift in how the state views suicide. A bill signed this week removes suicide as a crime under Virginia law, even though no one was ever actually punished for it. The change wo
Citizens Financial Group’s chief executive believes the next year will be better for the economy. He told investors in January that growth, job stability and falling inflation were likely by year‑end. His bank’s analysts also expected two more cuts from the Federal Reserve and a good financial pictu
A common hospital bug, Pseudomonas aeruginosa, often ignores many drugs and sticks together in protective layers called biofilms. Researchers made a new type of chemical that stops the bacteria from talking to each other, a process known as quorum sensing. This “talk‑stopper” is based on N‑acyl homo
The state’s mental‑health diversion plan, created in 2018 to keep people with serious illnesses out of jail, is under fire from prosecutors who say it lets dangerous offenders slip through the cracks. A high‑profile case that fuels this debate involved a man who was allowed to live in an LA shelt
Some actors disappear from movies and music for reasons that go beyond just wanting a break. Personal struggles, unfair treatment, or serious health issues can push them to leave the industry temporarily or even forever. For example, one singer who won Grammys and BRIT Awards suddenly vanished from
Smart money isn’t always smart when the bet is placed by AI. A fresh test throws cold water on the idea that today’s most advanced AI models can handle long-term financial tasks without human help. Researchers built a fake English Premier League betting market where AI agents had to grow their bankr
Boulder’s approach to managing its future has always stood out for balancing growth with environmental limits. But the latest draft of the Boulder Valley Comprehensive Plan takes a risky turn by loosening the strict rules that kept development in check for decades. One big change? Dropping the old n
